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Will Artificial intelligence become conscious?

Sunday, 7 January 2018 by System Administrator


Will artificial intelligence become conscious?
December 22, 2017
By Subhash Kak, Regents Professor of Electrical and Computer Engineering, Oklahoma State University
Forget about today’s modest incremental advances in artificial intelligence, such as the increasing abilities of cars to drive themselves. Waiting in the wings might be a groundbreaking development: a machine that is aware of itself and its surroundings, and that could take in and process massive amounts of data in real time. It could be sent on dangerous missions, into space or combat. In addition to driving people around, it might be able to cook, clean, do laundry — and even keep humans company when other people aren’t nearby.
A particularly advanced set of machines could replace humans at literally all jobs. That would save humanity from workaday drudgery, but it would also shake many societal foundations. A life of no work and only play may turn out to be a dystopia.
Conscious machines would also raise troubling legal and ethical problems. Would a conscious machine be a “person” under law and be liable if its actions hurt someone, or if something goes wrong? To think of a more frightening scenario, might these machines rebel against humans and wish to eliminate us altogether? If yes, they represent the culmination of evolution.
As a professor of electrical engineering and computer science who works in machine learning and quantum theory, I can say that researchers are divided on whether these sorts of hyperaware machines will ever exist. There’s also debate about whether machines could or should be called “conscious” in the way we think of humans, and even some animals, as conscious. Some of the questions have to do with technology; others have to do with what consciousness actually is.
Is awareness enough?
Most computer scientists think that consciousness is a characteristic that will emerge as technology develops. Some believe that consciousness involves accepting new information, storing and retrieving old information and cognitive processing of it all into perceptions and actions. If that’s right, then one day machines will indeed be the ultimate consciousness. They’ll be able to gather more information than a human, store more than many libraries, access vast databases in milliseconds and compute all of it into decisions more complex, and yet more logical, than any person ever could.
On the other hand, there are physicists and philosophers who say there’s something more about human behavior that cannot be computed by a machine. Creativity, for example, and the sense of freedom people possess don’t appear to come from logic or calculations.
Yet these are not the only views of what consciousness is, or whether machines could ever achieve it.
Quantum views
Another viewpoint on consciousness comes from quantum theory, which is the deepest theory of physics. According to the orthodox Copenhagen Interpretation, consciousness and the physical world are complementary aspects of the same reality. When a person observes, or experiments on, some aspect of the physical world, that person’s conscious interaction causes discernible change. Since it takes consciousness as a given and no attempt is made to derive it from physics, the Copenhagen Interpretation may be called the “big-C” view of consciousness, where it is a thing that exists by itself – although it requires brains to become real. This view was popular with the pioneers of quantum theory such as Niels Bohr, Werner Heisenberg and Erwin Schrödinger.
The interaction between consciousness and matter leads to paradoxes that remain unresolved after 80 years of debate. A well-known example of this is the paradox of Schrödinger’s cat, in which a cat is placed in a situation that results in it being equally likely to survive or die – and the act of observation itself is what makes the outcome certain.
The opposing view is that consciousness emerges from biology, just as biology itself emerges from chemistry which, in turn, emerges from physics. We call this less expansive concept of consciousness “little-C.” It agrees with the neuroscientists’ view that the processes of the mind are identical to states and processes of the brain. It also agrees with a more recent interpretation of quantum theory motivated by an attempt to rid it of paradoxes, the Many Worlds Interpretation, in which observers are a part of the mathematics of physics.
Philosophers of science believe that these modern quantum physics views of consciousness have parallels in ancient philosophy. Big-C is like the theory of mind in Vedanta – in which consciousness is the fundamental basis of reality, on par with the physical universe.
Little-C, in contrast, is quite similar to Buddhism. Although the Buddha chose not to address the question of the nature of consciousness, his followers declared that mind and consciousness arise out of emptiness or nothingness.
Big-C and scientific discovery
Scientists are also exploring whether consciousness is always a computational process. Some scholars have argued that the creative moment is not at the end of a deliberate computation. For instance, dreams or visions are supposed to have inspired Elias Howe‘s 1845 design of the modern sewing machine, and August Kekulé’s discovery of the structure of benzene in 1862.
A dramatic piece of evidence in favor of big-C consciousness existing all on its own is the life of self-taught Indian mathematician Srinivasa Ramanujan, who died in 1920 at the age of 32. His notebook, which was lost and forgotten for about 50 years and published only in 1988, contains several thousand formulas, without proof in different areas of mathematics, that were well ahead of their time. Furthermore, the methods by which he found the formulas remain elusive. He himself claimed that they were revealed to him by a goddess while he was asleep.
The concept of big-C consciousness raises the questions of how it is related to matter, and how matter and mind mutually influence each other. Consciousness alone cannot make physical changes to the world, but perhaps it can change the probabilities in the evolution of quantum processes. The act of observation can freeze and even influence atoms’ movements, as Cornell physicists proved in 2015. This may very well be an explanation of how matter and mind interact.
Mind and self-organizing systems
It is possible that the phenomenon of consciousness requires a self-organizing system, like the brain’s physical structure. If so, then current machines will come up short.
Scholars don’t know if adaptive self-organizing machines can be designed to be as sophisticated as the human brain; we lack a mathematical theory of computation for systems like that. Perhaps it’s true that only biological machines can be sufficiently creative and flexible. But then that suggests people should – or soon will – start working on engineering new biological structures that are, or could become, conscious.
Reprinted with permission from The Conversation
• Is anyone home? A way to find out if AI has become self-aware
• The Problem of AI Consciousness
Topics: AI/Robotics | Cognitive Science/Neuroscience

Biohybrid Nanobots for Medical Therapy

Sunday, 26 November 2017 by System Administrator

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Research ArticleMEDICAL ROBOTS
Multifunctional biohybrid magnetite microrobots for imaging-guided therapy
1. Xiaohui Yan1,
2. Qi Zhou2,
3. Melissa Vincent3,
4. Yan Deng4,
5. Jiangfan Yu1,
6. Jianbin Xu5,
7. Tiantian Xu1,
8. Tao Tang4,
9. Liming Bian1,5,
10. Yi-Xiang J. Wang6,
11. Kostas Kostarelos3 and
12. Li Zhang1,*
See all authors and affiliations
Science Robotics  22 Nov 2017:
Vol. 2, Issue 12, eaaq1155
DOI: 10.1126/scirobotics.aaq1155
• Article
• Figures & Data
• Info & Metrics
• eLetters
Magnetic microrobots and nanorobots can be remotely controlled to propel in complex biological fluids with high precision by using magnetic fields. Their potential for controlled navigation in hard-to-reach cavities of the human body makes them promising miniaturized robotic tools to diagnose and treat diseases in a minimally invasive manner. However, critical issues, such as motion tracking, biocompatibility, biodegradation, and diagnostic/therapeutic effects, need to be resolved to allow preclinical in vivo development and clinical trials. We report biohybrid magnetic robots endowed with multifunctional capabilities by integrating desired structural and functional attributes from a biological matrix and an engineered coating. Helical microswimmers were fabricated from Spirulina microalgae via a facile dip-coating process in magnetite (Fe3O4) suspensions, superparamagnetic, and equipped with robust navigation capability in various biofluids. The innate properties of the microalgae allowed in vivo fluorescence imaging and remote diagnostic sensing without the need for any surface modification. Furthermore, in vivo magnetic resonance imaging tracked a swarm of microswimmers inside rodent stomachs, a deep organ where fluorescence-based imaging ceased to work because of its penetration limitation. Meanwhile, the microswimmers were able to degrade and exhibited selective cytotoxicity to cancer cell lines, subject to the thickness of the Fe3O4 coating, which could be tailored via the dip-coating process. The biohybrid microrobots reported herein represent a microrobotic platform that could be further developed for in vivo imaging–guided therapy and a proof of concept for the engineering of multifunctional microrobotic and nanorobotic devices.
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Scaling down of microrobots and nanorobots able to be navigated into hard-to-reach tissues and other human body cavities currently inaccessible to available devices can offer miniaturized medical tools for biomedical applications such as disease monitoring, targeted drug delivery, minimally invasive surgery, and so on (1–6). However, miniaturization also brings fundamental engineering challenges such as power sourcing, precise actuation, integration of multifunctionality, and capability of post-injection recovery or biodegradation. To date, several strategies have been reported to address actuation and motion control, including application of external fields (e.g., magnetic, ultrasound, and light) (7–9), use of biological motors (10, 11), addition of chemical fuel (2, 12), or combinations of the above (13, 14). Among them, magnetic actuation has attracted particular attention because magnetic fields can continuously transmit power to the robotic devices in a wireless manner with high penetrating capacity through the human body harmlessly even at relatively high field strengths (1, 3–6, 15), which has been well justified by the widespread use of magnetic resonance (MR) imaging.
To enable magnetic actuation at the microscale and/or nanoscale, magnetic robots of various structures—such as rigid-flexible nanowires (13, 16, 17), microspheres (18, 19), ellipsoids (20, 21), helices (7, 22–25), filaments (26), and even arbitrary shapes (27, 28)—have been developed. Powered by an externally applied magnetic field of certain form (e.g., gradient, oscillating, rotating, or periodically varying), they can be remotely controlled to navigate a variety of complex geometries filled with biological media such as water, blood, serum, and mucus (1, 3–5, 7, 14, 16, 20–31). Furthermore, they have the ability to manipulate cellular or subcellular components in either a contact or noncontact fashion (7, 16, 19, 21, 26, 29). To be applied as versatile tools for in vivo applications, microrobots and nanorobots need to be equipped with further functionalities, such as traceability, biodegradability, and bioactivity. These can be realized with multiple engineering strategies, such as surface decoration, selection of chemical composition, structural design, or a combination of the above (7, 18, 22–24, 29–32). Among all functionalities, of particular interest are absence of cytotoxic response, biodegradability, chemical stability, noninvasive in vivo tracking, targeted drug release, and stimulus-responsive release (1–5, 7, 18, 22, 24, 29–32).
Nature offers a rich database of answers to scientific challenges and can inspire solutions. Through natural selection, organisms in real life have evolved sophisticated biological materials featuring not only diverse structures but also a wealth of functionalities, among others, including hydrophobicity/hydrophilicity, reversible adhesion, biodegradability, renewability, magnetotaxis, bioimpedance, fracture resistance, light weight, anti-reflection, and autofluorescence (33–41). Such nature-abundant functionalities provide interesting options for the engineering of navigable robotic devices (6, 10, 11, 42, 43). We hypothesized that magnetization of biological entities with certain specifications could allow fabrication of magnetic microrobots that incorporate the morphological and functional features from a biological matrix. The fabricated biohybrid agents could be considered essentially composite materials, benefiting from both the biological organic matter and the integrated magnetic component. Furthermore, the inherited functionalities could be tailored for designated applications by controlling the thickness of the magnetic coating during the magnetization process. Hereafter, we refer to this type of robotic agents as biohybrid magnetic robots (BMRs).
We report BMRs successfully fabricated from microalgae organisms, exhibiting intrinsic fluorescence (see section S1 and figs. S1 to S3), MR signals, natural degradability, and desirable cytotoxicity. These are all critical features in the design of imaging-guided microrobots for therapeutic inventions (1–5). First, to accomplish navigation in complex biological environments via feedback control, the motion of the microrobots and nanorobots needs to be tracked in vivo and monitored in real time, for which noninvasive multimodal imaging is an effective means. Second, such tiny robots should eventually either degrade themselves to be excreted or be removed without causing undesired side effects. Third, during navigation inside the body, they should not cause hazard to normal cells and, preferably, can inhibit the function of abnormal cells (e.g., malignant).
Microalgae, organisms with several million distinct species on Earth, have been widely studied and commercialized for their abundance of valuable chemical compositions, for example, pharmaceutically active compounds, high-quality proteins, and natural pigments (40, 44). To fabricate BMRs, an essential step is to magnetize microalgae while preserving their structural features and intrinsic functionalities. For that purpose, we used a facile dip-coating method that bonds Fe3O4 nanoparticles (NPs) onto biological surfaces (41, 45). We chose Fe3O4 NPs as the magnetic component for their MR contrast, agglomeration-free colloidal suspension, facile surface functionalization, and low cytotoxicity, which means negligible physiological effect on cell or tissue viability (5, 31, 46).
Previously, we have used Spirulina platensis (a microalgae subspecies that features helical shapes) as a biotemplate to fabricate magnetic microswimmers via three steps: deposition of magnetite precursors, annealing, and reduction (31). That work only harnessed the structural features of S. platensis to build a porous hollow microhelix suitable for cargo loading (the S. platensis in the core was removed during the annealing process). Here, we aimed to develop magnetic microrobots with integrated functionalities envisioned for imaging-guided therapy. Simply by coating the biological matrix S. platensis with Fe3O4 NPs in a controlled fashion, large quantities of such microrobots can be fabricated via a single cost-effective step, without the need of any functionalization processing (although further expansion of the microrobots’ functionalities are also possible owing to the easy functionalization nature of Fe3O4 NPs).
Figure 1A demonstrates the dip-coating process of S. platensis in Fe3O4 NP suspensions. The deposited Fe3O4 NPs firmly bonded to the surface of S. platensis and gradually formed a magnetite coating. For the mechanism and characterization of this process, refer to the Supplementary Materials (section S2, figs. S4 to S8, and table S1). As the field-emission scanning electron microscopy (FESEM) images in Fig. 1A show, the deposition of Fe3O4 NPs and therefore the coating thickness on S. platensis could be controlled by adjusting the dipping time. Consequently, the magnetic property of the microalgae BMR was also tailored (fig. S7), as were properties of the inherited functionalities such as autofluorescence, MR contrast, biodegradation, and bioactivity. Owing to the easy functionalization feature of Fe3O4, further extension of the BMR’s functions or designated loading of drugs is also possible by chemically decorating the Fe3O4 NPs through functional ligands (5, 31, 32, 46).

2018 Teens and Twenties

Friday, 24 November 2017 by System Administrator


Options for Safe, Secure and Legal Asset Preservation for Post-Resuscitation Access

The Ninth Annual Young Cryonicists Gathering

Teens & Twenties 9 - 2018:

Getting to Know You - You Getting to Know Each Other

Fri-Sun: May-4-6 • Hollywod, FL • Host: Life Extension Foundation